EC OPHTHALMOLOGY Mini Review Rediscovering Carbonic Anhydrase Inhibitors in Ophthalmology
نویسنده
چکیده
Background: Topical carbonic anhydrase inhibitors (CAI) are the commonly used pharmacologic agents as an ocular hypotensive in medical therapy of glaucoma. This traditional use is due to reduced aqueous production through decreased bicarbonate formation in ciliary body epithelium. Taken into account current economical burden worldwide, the well-known drugs are “rediscovered’ and repurposed. In this light of view CAI are highlighting new properties and new targets in modern ophthalmology. Objective: The objective of this review is to evaluate the evidence and discuss the rationale behind the recent suggestions that carbonic anhydrase inhibitors may be useful in therapy of retinitis pigmentosa.
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تاریخ انتشار 2016